David Cameron told MPs the report's evidence of systemic failure means 'we cannot say with confidence that failings of care are limited to one hospital'.
He added he was sorry the system had allowed 'horrific abuse to go unchecked and unchallenged' for so long.
'Hundreds of people suffered from the most appalling neglect and mistreatment,' he said.
'There were patients so desperate for water that they were drinking from dirty flower vases.
'And relatives were ignored or even reproached when pointing out the most basic things which could have saved their loves ones from horrific pain or even death.'Many were given the wrong medication, treated roughly, or left to wet themselves and to lie in urine for days.
'We can only begin to imagine the suffering endured by those whose trust in our health system was betrayed at their most vulnerable moment.
'On behalf of the Government and indeed our country, I am truly sorry.'
Read more: http://www.dailymail.co.uk/news/article-2274296/Mid-Staffs-report-Families-head-NHS-resign-damning-scandal.html#ixzz2KFsBswte
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